Evaluate Risk of Organ Transplant Rejection



A common outcome of a heart transplant is the heart being rejected by the recipient’s body. In fact, 20 percent of heart transplant mortality is linked to rejection of the donor heart by the recipient’s immune system.

Current practices for donor heart preservation allow a 3 to 4 hour window of organ viability. This timeframe does not allow for conventional tissue matching, a practice that determines if an organ will be compatible with the recipient. Upon FDA approval, Hibernicor’s Asporto heart preservation device will dramatically increase the viability window to allow for tissue matching.

Donor-to-recipient organ matching

Hibernicor’s freeware Reperio can be used to evaluate the risk of organ transplant rejection by a mismatch analysis. Using a unique algorithm, Reperio analyzes organ histocompatibility to allow transplant centers, laboratories and surgeons to independently compare how organ allocation leads to heterogeneity of organ HLA tissue matches which is directly related to short and long-term patient survival.

Try Reperio for free

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Download Reperio as a Microsoft Access database. It is updated with the 2007 HLA antigen values and split equivalences from the United Network for Organ Sharing. You can also view Hibernicor’s HLA Matching tool to determine the number of mismatches between a single donor and recipient.