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J Surg Res. 2021 Mar;259:242-252. doi: 10.1016/j.jss.2020.09.040. Epub 2020 Nov 26.
ABSTRACT
BACKGROUND: The optimal substrate for hypothermic machine perfusion preservation of donor hearts is unknown. Fatty acids, acetate, and ketones are preferred substrates of the heart during normothermic
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Am J Transplant. 2021 Apr;21(4):1597-1602. doi: 10.1111/ajt.16446. Epub 2021 Jan 2.
ABSTRACT
Heart transplantation from controlled donation after the circulatory determination of death (cDCDD) may help to increase the availability of hearts for transplantation. During 2020, four heart transplants
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Artif Organs. 2021 Jul;45(7):682-695. doi: 10.1111/aor.13894. Epub 2021 Mar 9.
ABSTRACT
The ever-widening gap between organ supply and demand has resulted in an organ shortage crisis that affects patients all over the world. For decades, static cold storage (SCS)
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J Extra Corpor Technol. 2020 Dec;52(4):303-313. doi: 10.1182/ject-2000034.
ABSTRACT
Ex situ heart perfusion (ESHP) has proven to be an important and valuable step toward better preservation of donor hearts for heart transplantation. Currently, few ESHP systems allow for a
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Magn Reson Med. 2021 Jun;85(6):3510-3521. doi: 10.1002/mrm.28639. Epub 2020 Dec 23.
ABSTRACT
PURPOSE: Increasing worldwide demand for cardiac transplantation has spurred new developments to increase the donor pool. Normothermic preservation of heart grafts for transplantation is an emerging strategy
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Sci Adv. 2021 Jan 8;7(2):eabe3005. doi: 10.1126/sciadv.abe3005. Print 2021 Jan.
ABSTRACT
Nanowarming of cryopreserved organs perfused with magnetic cryopreservation agents (mCPAs) could increase donor organ utilization by extending preservation time and avoiding damage caused by slow and nonuniform rewarming.
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Ann Thorac Surg. 2021 Jan 7:S0003-4975(21)00017-5. doi: 10.1016/j.athoracsur.2020.12.025. Online ahead of print.
ABSTRACT
BACKGROUND: Pediatric heart transplant (HTx) recipients with congenital heart defects require complex concomitant surgical procedures with the risk of prolonging the allograft’s ischemic time. Ex vivo
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Curr Treat Options Cardiovasc Med. 2021;23(5):28. doi: 10.1007/s11936-021-00906-5. Epub 2021 Mar 23.
ABSTRACT
PURPOSE OF REVIEW: With increasing survival of patients with stage D heart failure, the demand for heart transplantation has increased. The supply of donor hearts remains
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Can J Anaesth. 2021 May;68(5):661-671. doi: 10.1007/s12630-021-01926-2. Epub 2021 Feb 5.
ABSTRACT
Controlled donation after circulatory determination of death (DCD), where death is determined after cardiac arrest, has been responsible for the largest quantitative increase in Canadian organ donation
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Eur J Cardiothorac Surg. 2021 Mar 30:ezab139. doi: 10.1093/ejcts/ezab139. Online ahead of print.
ABSTRACT
OBJECTIVES: Hearts donated after circulatory determination of death are usually preserved with normothermic machine perfusion prior to transplantation. This type of preservation is costly, requires
