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[Approval] Blood Cardioplegia Induction, Perfusion Storage and Graft Dysfunction in Cardiac Xenotransplantation

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Front Immunol. 2021 Jun 9;12:667093. doi: 10.3389/fimmu.2021.667093. eCollection 2021.

ABSTRACT

BACKGROUND: Perioperative cardiac xenograft dysfunction (PCXD) describes a rapidly developing loss of cardiac function after xenotransplantation. PCXD occurs despite genetic modifications to increase compatibility of the heart. We report

[Approval] Machine perfusion of donor heart with normothermic blood versus hypothermic HTK in preserving coronary endothelium in a porcine model of DCD

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Ann Palliat Med. 2020 Jul;9(4):1476-1487. doi: 10.21037/apm-20-131. Epub 2020 Jul 13.

ABSTRACT

BACKGROUND: Both machine perfusion (MP) of donor hearts with autologous blood and crystalloid perfusates have advantages and disadvantages. Currently, which of the aforementioned preservation strategies can better