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Xenotransplantation. 2021 Jan;28(1):e12636. doi: 10.1111/xen.12636. Epub 2020 Aug 25.

ABSTRACT

BACKGROUND: Successful preclinical transplantations of porcine hearts into baboon recipients are required before commencing clinical trials. Despite years of research, over half of the orthotopic cardiac xenografts were lost

Front Immunol. 2020 Jul 28;11:1621. doi: 10.3389/fimmu.2020.01621. eCollection 2020.

ABSTRACT

Introduction: Many donor organs contain significant leukocyte reservoirs which upon transplantation activate recipient leukocytes to initiate acute rejection. We aimed to assess whether non-ischemic heart preservation via ex vivo

Braz J Cardiovasc Surg. 2020 Aug 1;35(4):484-489. doi: 10.21470/1678-9741-2019-0264.

ABSTRACT

OBJECTIVE: To investigate the effect of Shenfu (SF) injection on donor heart preservation.

METHODS: Twelve pigs were randomly divided into SF group (n=6) and control group (n=6). After eight hours

Transplantation. 2021 Jul 1;105(7):1530-1538. doi: 10.1097/TP.0000000000003476.

ABSTRACT

BACKGROUND: Normothermic ex situ liver perfusion (NEsLP) reduces reperfusion injury of donation after circulatory death (DCD) grafts and optimizes graft function. The goal of our study was to elucidate how NEsLP impacts

J Clin Exp Hepatol. 2020 Sep-Oct;10(5):462-466. doi: 10.1016/j.jceh.2019.12.007. Epub 2020 Jan 7.

ABSTRACT

INTRODUCTION: We describe our technique of ex vivo organ perfusion and procurement in donation after deceased brain death (DBD) donors.

MATERIAL AND METHODS: This technique comprises warm

PLoS One. 2020 Oct 12;15(10):e0239604. doi: 10.1371/journal.pone.0239604. eCollection 2020.

ABSTRACT

Demand for heart transplants far exceeds supply of donated organs. This is attributed to the high percentage of donor hearts that are discarded and to the narrow six-hour time

J Heart Lung Transplant. 2020 Dec;39(12):1408-1416. doi: 10.1016/j.healun.2020.08.021. Epub 2020 Sep 4.

ABSTRACT

BACKGROUND: The aim of this study was to match clinical outcomes of heart transplantation (HTx) against histopathologic and ultrastructural characteristics of marginal grafts preserved by cold

Clin Transplant. 2020 Dec;34(12):e14122. doi: 10.1111/ctr.14122. Epub 2020 Nov 22.

ABSTRACT

BACKGROUND: Few studies directly compare outcomes between the most commonly used preservation solutions in pediatric heart transplantation in a large cohort of recipients. The purpose of this study

Sci Rep. 2020 Oct 16;10(1):17531. doi: 10.1038/s41598-020-73150-9.

ABSTRACT

Xenotransplantation using pig organs has achieved survival times up to 195 days in pig orthotopic heart transplantation into baboons. Here we demonstrate that in addition to an improved immunosuppressive regimen, non-ischaemic

J Cardiothorac Surg. 2020 Oct 27;15(1):323. doi: 10.1186/s13019-020-01367-w.

ABSTRACT

BACKGROUND: Organ Care System (OCS) minimizes the cold ischemic time and allows for optimization of logistics and meticulous recipient preparation. Impact of normothermic ex-vivo preservation using OCS compared with cold